American Airlines flights to Panama City

The best American Airlines flight deals to Panama City

Looking for a last-minute deal or the best direct flight? Find the biggest savings on one-way and round-trip flights to Panama City with American Airlines.

Find the cheapest time to fly to Panama City with American Airlines

Flexible on travel dates? Here's when plane tickets are cheapest.

Find which Panama City airports American Airlines flies to

Compare routes to Panama City below. You may find an airport to fly into that's cheaper, faster, or easier.

Flying to Panama City with American Airlines

The things to know before you go.
Cheapest flight found$9,280
Cheapest month to flyOctober

Flying to Panama City with American Airlines: FAQs

The average American Airlines flight time from Mexico to Panama City is 4 hours and 27 minutes.
At the moment, Copa, Emirates, Aeromexico, AeroMexico Connect and MasAir all fly to Panama City too.
American Airlines currently also flies to Dallas Fort Worth International, Chicago O'Hare International and Charlotte Douglas.
Although it's difficult to get an accurate idea of when American Airlines flights to Panama City are cheapest, the lowest fares are currently for departures in November.